Tirzepatide price in October 2026: $299–$449 a month as Zepbound
As of October 19, 2026, tirzepatide is sold as two FDA-approved Eli Lilly brands and as compounded versions. Zepbound costs $299 to $449 a month self-pay on LillyDirect. Mounjaro lists at $1,112.16 per fill, or $499 with Lilly's card if a plan won't cover it. Compounded tirzepatide is advertised from $90. Source: Eli Lilly and Company.
Every tirzepatide product and its price
| Product | Status | Published prices |
|---|---|---|
| ZepboundWeekly injection: single-dose vial, four-dose KwikPen, or single-dose autoinjector pen | FDA-approved for chronic weight management and for moderate-to-severe obstructive sleep apnea in adults with obesity[1] |
|
| MounjaroWeekly single-dose pen (2.5–15 mg) | FDA-approved for type 2 diabetes[5]. It is not approved for weight loss; Zepbound is the tirzepatide product for that. | |
| Compounded tirzepatideUsually a weekly injection from a vial; some programs sell dissolving tablets | Not FDA-approved. Not a generic of Zepbound or Mounjaro. |
Compounded, not FDA-approved. Compounded drugs are made by state-licensed pharmacies or outsourcing facilities. They are not FDA-approved, are not generic versions of Wegovy, Ozempic, Zepbound or Mounjaro, and the FDA has not reviewed them for safety, effectiveness or quality.
Why does tirzepatide cost different amounts?
Because the price belongs to the product, not the molecule. Zepbound is Lilly's tirzepatide for weight: FDA-approved for chronic weight management and for moderate-to-severe obstructive sleep apnea in adults with obesity[1] Lilly sells it to cash payers through LillyDirect at $299 to $449 per 28 days, depending on dose[2]. Mounjaro is the same ingredient for type 2 diabetes. FDA-approved for type 2 diabetes[5]. It is not approved for weight loss; Zepbound is the tirzepatide product for that. We found no LillyDirect self-pay vial for it, so its price is the list price or the savings-card price[6].
Compounded tirzepatide is a third thing again. Compounded drugs are made by state-licensed pharmacies or outsourcing facilities, are not FDA-approved and are not generic versions of Zepbound or Mounjaro. The 7 telehealth programs we track advertise it from $90 to $389 a month, usually with a membership or a long-term plan[8].
What is the cheapest way to get tirzepatide?
It depends on coverage. The lowest published price for each route, from the product pages:
- Commercial plan that covers it: $25 for Zepbound with Lilly's savings card[3], and $25 for Mounjaro[6].
- Medicare: $50 a month for the Zepbound KwikPen through the Medicare GLP-1 Bridge, for eligible Part D enrollees[4].
- No coverage, brand-name: $299 a month for Zepbound 2.5 mg on LillyDirect, $449 at 7.5 mg and above with on-time refills[2].
- Compounded: advertised from $90, membership extra; read what that means before comparing it with an FDA-approved product.
The full route-by-route list, including semaglutide and orforglipron, is on cheapest GLP-1.
Is there a generic tirzepatide?
No program we track sells an FDA-approved generic tirzepatide; every brand-name offer we track is Zepbound or Mounjaro from Lilly. Compounded tirzepatide is sometimes described online as "generic", but it is not a generic version of either brand and is not FDA-approved. The FDA says tirzepatide does not currently appear on its drug shortage list[11]. See is compounded tirzepatide legal?
Prices are what manufacturers and programs publish. Your prescriber decides which product and dose fit you; GLP Observer compares prices only.
Questions people ask
How much does tirzepatide cost per month without insurance?
As Zepbound from LillyDirect, $299 at 2.5 mg, $399 at 5 mg and $449 at 7.5–15 mg per 28 days with on-time refills (checked October 19, 2026).
Is Zepbound cheaper than Mounjaro?
For cash payers, yes: Zepbound is $299–$449 self-pay, while uncovered Mounjaro is $499 a fill with Lilly's card and $1,112.16 at list. They contain the same ingredient but are approved for different uses.
How much is compounded tirzepatide?
The 7 programs we check advertise it from $90 to $389 a month; the median lowest price is $169. It is not FDA-approved.
Sources
Every price above links to one of these pages. We loaded each one and saved a copy on the date shown.
- Zepbound (tirzepatide) now available in multi-dose KwikPen . Eli Lilly and Company, published Feb 23, 2026. Checked .https://investor.lilly.com/news-releases/news-release-details/zepbound-tirzepatide-most-prescribed-weight-management
- Zepbound on LillyDirect (vial and KwikPen self-pay prices) . Eli Lilly and Company. Checked .https://www.lilly.com/lillydirect/zepbound
- Zepbound cost information (list price and direct-to-patient price) . Eli Lilly and Company. Checked .https://pricinginfo.lilly.com/zepbound
- What to Know About the BALANCE Model for GLP-1s in Medicare and Medicaid and the Medicare GLP-1 Bridge . KFF, published May 11, 2026. Checked .https://www.kff.org/medicare/what-to-know-about-the-balance-model-for-glp-1s-in-medicare-and-medicaid/
- Hims weight loss: medications and prices . Hims & Hers Health. Checked .https://www.hims.com/weight-loss
- Mounjaro savings and coverage . Eli Lilly and Company. Checked .https://mounjaro.lilly.com/savings-resources
- Mounjaro cost information (list price) . Eli Lilly and Company. Checked .https://pricinginfo.lilly.com/mounjaro
- Ivím Health: compounded GLP-1 prices and membership . Ivím Health. Checked .https://www.ivimhealth.com/
- FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize . U.S. Food and Drug Administration. Checked .https://www.fda.gov/drugs/drug-alerts-and-statements/fda-clarifies-policies-compounders-national-glp-1-supply-begins-stabilize